Form 6-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO

RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of March 2018

Commission File Number: 001-38396

BIOFRONTERA AG

(Registrant’s name / Translation of registrant’s name into English)

Hemmelrather Weg 201, D-51377 Leverkusen Germany

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F [X] Form:40-F [ ]

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): N/A

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): N/A

EXHIBITS

Exhibit Number		Description

99.1		Biofrontera AG: Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	BIOFRONTERA AG

	By:	/s/ Hermann Lübbert
	Name:	Hermann Lübbert
	Title:	Chief Executive Officer

	By:	/s/ Thomas Schaffer
	Name:	Thomas Schaffer
	Title:	Chief Financial Officer

Date: March 28, 2018

Biofrontera AG: Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them 28.03.2018 1. Details of the person discharging managerial responsibilities / person closely associated a) Name
Title:
First name:	Kevin
Last name(s):	Weber

2. Reason for the notification a) Position / status
Position:	Member of the administrative or supervisory body

b) Initial notification

3. Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor a) Name
Biofrontera AG

b) LEI
391200D6GFSVFGFQTL13

4. Details of the transaction(s) a) Description of the financial instrument, type of instrument, identification code
Type:	Share
ISIN:	DE0006046113

b) Nature of the transaction
Acquisition

c) Price(s) and volume(s)
Price(s)	Volume(s)
6.20 EUR	31000.00 EUR

d) Aggregated information
Price	Aggregated volume
6.2000 EUR	31000.0000 EUR

e) Date of the transaction
2018-03-26; UTC+1

f) Place of the transaction
Name:	Xetra
MIC:	XETR

Company:	Biofrontera AG
	Hemmelrather Weg 201
	51377 Leverkusen
	Germany
Internet:	www.biofrontera.com